Table 3.
Any HPV infection |
Any HR-HPV infection |
|||
Variable | HR (95% CI) | aHRa (95% CI) | HR (95% CI) | aHRa (95% CI) |
Age (y) | ||||
<26 | 1.0 | 1.0 | 1.0 | 1.0 |
26–30 | 0.78 (.57–1.06) | 0.79 (.58–1.07) | 0.92 (.59–1.40) | 1.08 (.69–1.68) |
31–33 | 0.87 (.64–1.18) | 0.88 (.65–1.20) | 0.92 (.59–1.42) | 0.98 (.64–1.50) |
34–38 | 0.79 (.57–1.09) | 0.86 (.62–1.18) | 0.71 (.44–1.15) | 0.83 (.52–1.33) |
Study site | ||||
North | 1.0 | 1.0 | 1.0 | 1.0 |
Northeast | 0.73 (.54–1.00) | 0.86 (.62–1.18) | 0.62 (.39–.98) | 0.92 (.56–1.50) |
South | 0.94 (.72–1.24) | 0.99 (.75–1.31) | 0.97 (.66–1.44) | 1.15 (.78–1.70) |
Central | 0.72 (.54–.95) | 0.73 (.54–.98) | 0.65 (.44–.98) | 0.87 (.57–1.34) |
Contraceptive use | ||||
NHC | 1.0 | 1.0 | 1.0 | 1.0 |
DMPA | 0.99 (.74–1.33) | 0.75 (.50–1.13) | 0.86 (.57–1.31) | 0.78 (.45–1.37) |
COC | 0.78 (.61–.99) | 0.67 (.49–.93) | 0.69 (.49–.98) | 0.58 (.37–.94) |
No. of partners L6M | ||||
0 | 1.0 | 1.0 | 1.0 | 1.0 |
1 | 0.78 (.43–1.42) | 1.12 (.48–2.58) | 0.52 (.13–2.10) | 2.45 (.11–53.0) |
>1 | 1.46 (.56–3.82) | 1.02 (.37–2.85) | 0.70 (.13–3.70) | 3.13 (.13–75.0) |
No. of lifetime partners | ||||
1 | 1.0 | 1.0 | 1.0 | 1.0 |
2 | 0.65 (.48–.87) | 0.61 (.45–.82) | 0.82 (.55–1.22) | 0.86 (.56–1.31) |
3 | 0.91 (.64–1.31) | 0.84 (.58–1.21) | 0.93 (.57–1.53) | 0.99 (.59–1.66) |
≥4 | 1.11 (.84–1.48) | 1.06 (.80–1.39) | 1.09 (.77–1.53) | 1.04 (.69–1.57) |
Cervical ectopy | ||||
No | 1.0 | 1.0 | 1.0 | 1.0 |
Yes | 0.88 (.70–1.11) | 0.85 (.62–1.17) | 0.78 (.56–1.09) | 0.76 (.49–1.18) |
HPV infection type | ||||
Prevalent | 1.0 | 1.0 | 1.0 | 1.0 |
Incident | 2.86 (2.24–3.65) | 3.25 (2.55–4.15) | 2.78 (1.93–3.90) | 3.01 (2.08–4.34) |
Abbreviations: aHR, adjusted hazard ratio; CI, confidence interval; COC, combined oral contraception; DMPA, depomedroxyprogesterone acetate; HPV, human papillomavirus; HR, hazard ratio; HR-HPV, HPV types considered to be high risk; L6M, last 6 months; NHC, nonhormonal contraception.
All variables mutually adjusted for.