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. 2011 Aug 31;13(3):e64. doi: 10.2196/jmir.1775

Table 4.

Prevalence of safety issues for top 20 products advertised direct to consumers, 2009

Drug Safety warninga
Lipitor Subject to recall; other safety notification
Ablify Black box warning; subject to recall
Advair Diskus Black box warning
Cymbalta Black box warning
Cialis Other safety notification
Lyrica None
Plavix Black box warning; subject to recall; other safety notification
Symbicort Black box warning; other safety notification
Ambien CR Other safety notification
Crestor Other safety notification
Viagra Other safety notification
Pristiq Black box warning; other safety notification
Flomax Other safety notification
Chantix Black box warning
Yaz Black box warning; other safety notification
Enbrel Black box warning; subject to recall; other safety notification
Celebrex Black box warning
Boniva Other safety notification
Spiriva Subject to recall
Caduet None

a “Other safety warnings” include voluntary recalls, counterfeit warnings, warnings on contraindications, warnings about combining with other drugs, and other US Food and Drug Administration-issued alerts.