Table 2.

Features of poor prognosis and disease activity for a history of arthritis of 5 or more joints

Features of poor prognosis (must satisfy 1)

Arthritis of the hip (23---25) or cervical spine

Positive rheumatoid factor (5,23,28,30,32,33) OR anti---cyclic citrullinated peptide (33,34) antibodies

Radiographic damage (erosions or joint space narrowing by radiograph) (31)

Disease activity levels

Low disease activity (must satisfy all)

4 or fewer active joints

Erythrocyte sedimentation rate or C-reactive protein level normal

Physician global assessment of overall disease activity <4 of 10

Patient/parent global assessment of overall well-being <2 of 10

Moderate disease activity (does not satisfy criteria for low or high activity)

1 or more features greater than low disease activity level AND fewer than 3 features of high disease activity

High disease activity (must satisfy at least 3)

8 or more active joints

Erythrocyte sedimentation rate or C-reactive protein level greater than twice upper limit of normal

Physician global assessment of overall disease activity ≥7 of 10

Patient/parent global assessment of overall well-being ≥5 of 10