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. Author manuscript; available in PMC: 2011 Nov 22.
Published in final edited form as: Am J Physiol Gastrointest Liver Physiol. 2008 Apr 17;294(6):G1441–G1449. doi: 10.1152/ajpgi.00588.2007

Fig. 2.

Fig. 2

Effects of subdiaphragmatic (subdiph) vagotomy on the VMR to colorectal distension (CRD) in conscious rats. Data were collected from 8 sham-operation control rats and 10 rats after vagotomy. The VMR was quantified as the number of abdominal muscle contractions (A) and the mean amplitude, expressed as the area under the curve (AUC) after baseline subtraction (B). CRD evoked a dose-dependent increase in VMR in control sham operation rats. Chronic subdiaphragmatic vagotomy produced a marked increase in the number of abdominal muscle contractions. *P < 0.05 compared with sham operation. ANOVA showed a significant effect for distension level, as well as a significant interaction between distension level and group (*P < 0.05). Stimulus-response functions were shifted to the left in vagotomized rats, indicating group differences in the VMR response. Values are means ± SE.