Figure 2.

Prolonged survival in glucose-6-phosphatase (G6Pase) (−/−) mice following adeno-associated virus (AAV) vector administration. Affected mice did not survive until 1 month of age (data not shown), unless the AAV vector was administered at 12 days of age. Kaplan–Meier survival analysis following (a) high vector dose (1 × 10¹³ vp/kg, except AAV2 = 5 × 10¹² vp/kg), or (b) low vector dose (2 × 10¹² vp/kg) was administered as indicated. (c) Body weight for G6pase (−/−) and G6pase (+/+) mice at the indicated age. Mean ± SD are shown.