Figure 2.
Gene transfer and transduction efficiency in infant rhesus monkeys. Data from previously published adolescent rhesus monkeys (d7-Adole and d35-Adole) administered the same vector at the same dose7,23 are included for comparison. (a) Vector genome copies in liver. (b) Vector genome copies in spleen. (c) Quantitative morphometric analysis of the transduction efficiency based on percent transduction of liver area. (d) Quantification of EGFP in liver lysates by ELISA. Horizontal lines show the mean levels for each group. EGFP, enhanced green fluorescent protein; ELISA, enzyme-linked immunosorbent assay; GC, genome copies.