Figure 6.
Detection of AAV8 capsid protein in the germinal centers of infant rhesus monkey spleens. Spleens were collected at 7 (a), 35 (b), or 45 (c) days after vector administration. Immunostaining showed the presence of capsid protein (red) in germinal centers in some animals (#N2, #N3, #N7, #N8). Samples are counterstained with DAPI (shown in blue) to visualize nuclei. Bar = 100 µm. AAV, adeno-associated virus.