Table 2. Cost data used in model.
Monthly Costs |
Monthly Cost Range* |
|
---|---|---|
Baseline Health State Costs | ||
| ||
Baseline average monthly outpatient costs for patient with compensated cirrhosis | 63 | 31-126 |
Baseline average monthly costs for subjects with permanent contraindication to transplant | 777 | 389-1554 |
Baseline average monthly costs for recipients post transplantation | 772 | 386-1544 |
| ||
Cost Tolls for Specific Events | ||
| ||
Average cost of TIPS procedure. Includes revisions, complications, hospitalizations, imaging, and outpatient follow-up |
18,192 | 9,096-36,384 |
Average cost of an episode of SBP. Includes treatment, hospitalization, complications, and imaging |
10,248 | 5,124-20,496 |
Average cost of ascites and peripheral edema requiring admission to the hospital | 6,197 | 3,098-12,394 |
Average cost of encephalopathy admission. | 4,297 | 2,148-8,594 |
Average monthly cost of HCC. Includes imaging, procedures, and follow-up | 3,755 | 1,877-7,510 |
Average cost of variceal bleeding. Includes hospitalization, procedures, and follow-up | 11,964 | 5,892-23,928 |
One-time cost of DDLT procedure. Includes deceased donor expenses and organ acquisition costs from OPO, hospitalization, and pharmacy (126). |
103,806 | 51,903-207,612 |
One-time cost of LDLT procedure. Includes workup costs for 1.23 potential donors (49, 50), donor procedure without complications, hospitalization, and pharmacy (126). Donor costs are normalized to DDLT OPO charges to avoid double-charging living donors. The actual estimated costs for one time live donor procedure without complications is $129,144 (see text). |
103,806 | 51,903-207,612 |
One-time cost for donor having major complications. Includes hospitalization, procedures, pharmacy, and follow-up. |
16,892 | 8,446-33,784 |
One-time cost for donor death. Estimated at 75% of the cost of a major complication. | 12,669 | 6,335-25,338 |
One-time cost for recurrent disease causing graft failure. This is only applied to subjects not eligible for re-transplantation. Based on costs incurred for care when transplant is contraindicated. |
4,662 | 2,331-9,324 |
Average cost for post-transplant subjects with non-biliary infectious complications. Includes hospitalization, imaging, pharmacy, and follow-up. |
6,952 | 3,476-13,904 |
Average cost for post transplant recipients that require non-transplant re-operation. Based on the cost of laparotomy. |
16,892 | 8,446-33,784 |
Average cost for post-transplant subjects with clinically significant biliary complications. Includes cost associated with chronic biliary strictures, and 2 ERCP’s. (104) |
7,292 | 3,646-14,584 |
One-time cost of post-transplant recipients that require non-transplant reoperation for biliary complication. Does not include ERCP costs. Based on the cost of laparotomy. |
18,607 | 9,303-37,214 |
Average cost of post-transplant treatment of acute rejection. Includes hospitalization, procedures, pharmacy, and follow-up. |
6,798 | 3,339-13,596 |
Ranges are derived as 50% and 200% of calculated costs.