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. Author manuscript; available in PMC: 2011 Nov 22.
Published in final edited form as: Liver Transpl. 2009 Feb;15(2):148–162. doi: 10.1002/lt.21671

Table 3.

Utility data used in the model.

Base Case Utility Utility Range Sources
Baseline Health State Utilities

Utility of compensated cirrhosis (Childs B) 0.71 0.44-0.98 (40-47)
Utility of decompensated cirrhosis (Childs C) 0.56 0.30-0.67 (40-47)
Utility of recipient post liver transplantation 0.80 0.63-0.87 (41, 43, 45, 47, 127)
Utility penalty accrued every month after transplant when donor
dies secondary to donation complication. Donors are assumed
to be in perfect health before donation.
Recipient utility – 1.0 0.75-1.0 Expert opinion
Utility penalty accrued every month after transplant when donor
has major complications secondary to donation complication
(128). Donors are assumed to be in perfect health before
donation.
Recipient utility – 0.3 0.25-1.0 Expert opinion

Utility Tolls for Specific Events Percent Toll From
Baseline

Monthly utility penalty for refractory ascites −25% 0-80% (44)
One-time utility penalty from TIPS −25% 0-80% (42)
One-time utility penalty for SBP. Based on utility for refractory
ascites.
−25% 0-80% (44)
Monthly utility penalty for HCC −10% 0-50% (41, 43, 44)
Monthly utility penalty for encephalopathy −25% 0-80% (42, 44)
Monthly utility penalty for variceal bleeding −25% 0-80% (42, 44)
One-time utility penalty for recent major surgery −20% 0-80% (58)
Monthly utility penalty for major complication of transplantation −25% 0-80% (41, 43, 45, 47, 127)
One-time utility penalty for undergoing DDLT −50% 25-75% (41, 43, 45, 47, 127)
One-time utility penalty for undergoing LDLT. Includes
combined donor and recipient penalties
−75% 25-90% (41, 43, 45, 47, 127)
and expert opinion