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. Author manuscript; available in PMC: 2011 Nov 22.
Published in final edited form as: Liver Transpl. 2009 Feb;15(2):148–162. doi: 10.1002/lt.21671

Table 4. Model validation and survival data after ten year, 1000 subject trial.

Results from a 120-month Monte Carlo simulation of 1,000 theoretical subjects with base case values for all variables.

Variable No
transplant
available
Listed for
DDLT
Listed for
DDLT with
LDLT
available
Mean cost per patient, 2002 USD 65,068 151,613 208,149
Mean unadjusted lifespan (years) 3.1 6.4 7.3
Mean quality adjusted lifespan (QALY) 1.9 4.4 4.9
Number receiving DDLT (primary or retransplant) - 687 233
Number receiving LDLT (primary) - - 715
Number dead after 1 year 175 158 136
Number dead after 5 years 630 335 256
Number dead after 10 years 964 454 397
Number receiving primary transplant at one year - 309 520
Number receiving primary transplant at five years - 516 662
Number dead pre-transplant or on waitlist* (%) 964 309 (30.9) 112 (11.2)
Mean cost to prevent one pre-transplant death, 2002 USD - 122,516 199,942
Number dead after transplant (%) - 145 (14.5) 285 (28.5)
Living donor deaths (%) - - 2 (0.2)
Living donor serious complications, excluding deaths (%) - - 17 (2.4)
*

This represents a 10 year cumulative mortality for the entire cohort. The yearly mortality rate on the waiting list is roughly one-tenth of this value.