Table 1.

Onset of neurological features [yrs] in members of the AMRF pedigree depicted in Figure 1 and Figure 2

patient [pedigree number]	sex	age of onset	action myoclonus	tonic clonic seizures	ataxia	demyelinating polyneuropathy	hearing impairment	age at death [yrs]
II:1	m	14	14	20	14	+	NA	31
II:6	f	20	20	20	20	+	26	34
II:3	m	20	26	32	20	+	NA	38
II:5	f	14	-	14	-	unclear	-	alive

If known, the age of onset [yrs] of a feature is indicated; "+" = present but age of onset unknown; "-" = absent; "NA" = not assessed.