Table 2. Correlation of CCA test with schistosome infection and microhematuria (n = 526).
Test | Association | Adjusted OR (95% CI) | P-value |
CCA-A | |||
(color categories) | S. mansoni egg count | 1.07 (1.05, 1.09) | <0.001 |
S. mansoni infection categories | 36.50 (27.35, 48.77) | <0.001 | |
CCA-A (pos/neg) | S. haematobium egg count | 1.09 (0.97, 1.21) | 0.121 |
Hematuria trace | 0.39 (0.09, 1.64) | 0.200 | |
Hematuria moderate (2+) | 1.09 (0.17, 7.00) | 0.923 | |
Hematuria heavy (3+) | 0.90 (0.12, 6.99) | 0.195 | |
CCA-B | |||
(color categories) | S. mansoni egg count | 1.03 (1.01, 1.04) | <0.001 |
S. mansoni infection categories | 25.20 (15.83, 39.95) | <0.001 | |
CCA-B (pos/neg) | S. haematobium egg count | NA* | |
Hematuria trace | NA* | ||
Hematuria moderate (2+) | NA* | ||
Hematuria heavy (3+) | NA* |
*NA: not applicable due to the small number of children without S. mansoni infection.
Ordinal logistic regression was used to assess the correlation between CCA test categories (0, 1+, 2+, and 3+) as outcome and S. mansoni egg count or S. mansoni infection categories (low, moderate, and heavy) as explanatory variable. Category “low” was used as baseline for comparison of other categories.
Logistic regression was applied to assess the correlation between CCA test results expressed as binary variables (positive/negative) and S. haematobium egg counts and microhematuria categories (trace, 1+, 2+, and 3+). Category “1+” was used as baseline for comparison of other categories.