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. 2011 Nov 22;5(11):e1384. doi: 10.1371/journal.pntd.0001384

Table 2. Correlation of CCA test with schistosome infection and microhematuria (n = 526).

Test Association Adjusted OR (95% CI) P-value
CCA-A
(color categories) S. mansoni egg count 1.07 (1.05, 1.09) <0.001
S. mansoni infection categories 36.50 (27.35, 48.77) <0.001
CCA-A (pos/neg) S. haematobium egg count 1.09 (0.97, 1.21) 0.121
Hematuria trace 0.39 (0.09, 1.64) 0.200
Hematuria moderate (2+) 1.09 (0.17, 7.00) 0.923
Hematuria heavy (3+) 0.90 (0.12, 6.99) 0.195
CCA-B
(color categories) S. mansoni egg count 1.03 (1.01, 1.04) <0.001
S. mansoni infection categories 25.20 (15.83, 39.95) <0.001
CCA-B (pos/neg) S. haematobium egg count NA*
Hematuria trace NA*
Hematuria moderate (2+) NA*
Hematuria heavy (3+) NA*

*NA: not applicable due to the small number of children without S. mansoni infection.

Ordinal logistic regression was used to assess the correlation between CCA test categories (0, 1+, 2+, and 3+) as outcome and S. mansoni egg count or S. mansoni infection categories (low, moderate, and heavy) as explanatory variable. Category “low” was used as baseline for comparison of other categories.

Logistic regression was applied to assess the correlation between CCA test results expressed as binary variables (positive/negative) and S. haematobium egg counts and microhematuria categories (trace, 1+, 2+, and 3+). Category “1+” was used as baseline for comparison of other categories.