Skip to main content
. 2011 Nov 22;5(11):e1371. doi: 10.1371/journal.pntd.0001371

Table 1. Thirty-two G. pallidipes secretome proteins uniquely expressed in hypertrophied salivary glands.

Mol. wt range Description of the proteins expressed in high abundance in hypertrophied salivary glands
Protein Name Accession No. Functional annotation
<26 kDa Bis-(5′-nucleosyl)-tetraphosphatase XP_001969373.1 DNA replication, metabolic stress and apoptosis
Niemann-Pick TypeC-2 ADD20212.1 Mesoderm development
RNA polymerase II - BTF3 ADD19794.1 Transcription
deoxyUTP-pyrophosphatase ADD20717.1 Chromosomal integrity
Transitional ER ATPase XP_002016299.1 Molecular chaperones
ADP-ribosylation factor 1 ADE42873.1 Vesicle coat protein assembly
DNA replication factor/protein phosphatase inhibitor SET/SPR-2 ADD19576.1 Movement of histones; nucleasome assembly; chromatin fluidity
GTPase -binding nuclear protein Ran/TC4/gSP1 ADD18812.1 Nuclear transport and DNA replication
Cu/Zn-superoide dismutase ADD19264.1 REDOX processes
26–43 kDa Ras-like GTP-binding protein Rho1 ADD18925.1 Control of cytoskeletal changes
Proteasome activator complex subunit 3 ADD19370.1 Binds to 20S proteasome
Aldo/keto reductase ADD18539.1 Oxidoreductase activities
26S proteasome non-ATPase regulatory complex ADD18827.1 Integrity of 26S proteasome complex
Quiescin-sulfhydryl oxidase4 XP_002048727.1 Localized in high concentrations in cells with heavy secretory load
43–55 kDa Serine protease inhibitor4 ABC25075.1 Chaperoning; Toll signalling
60s acidic ribosomal protein P0 ADD19996.1 Proteins synthesis
S-adenosylmethionine synthetase ADD19751.1 Supplies metabolic methyl groups by catalyzing synthesis of AdoMet
ATP-dependent RNA helicase XP_001968815.1 Splicing and ribosome biogenesis
Vacuolar ATPase-S1 Ac45 ADD18511.1 REDOX; NAD/NADH-binding
Imaginal growth factor-3 ABC25095.1 Chitinase-related GH18; interaction with surface glycoproteins
Hsp-cognate70Cb CAB38172.2 Protein folding
Yellow protein precursor ADD19747.1 Controls adult pigmentation
>55 kDa Catalase ADD20421.1 Protection from peroxides
Hsp70/Hsp90 organizing protein ADD19147.1 Protein-protein interactions; chaperoning; transcription; protein transport complexes
Juvenile hormone esterase ADD18773.1 Hydrolase
Hsp60 (GroEL chaperonin) ADD20133.1 Productive protein folding
Angiotensin-converting-enzyme XP_002002462.1 Membrane-located metallopeptidase
Amidophosphoribosyltransferase XP_002083899.1 Purine biosynthesis
Lysosomal-α-manosidase ADD18519.1 Carbohydrate metabolism
C1-Tetrahydrofolate synthase ADD18346.1 Carbon metabolism
Endocytosis/signalling protein EHD1 ADD19069.1 Endocytosis; vesicle transport; signal transduction
Gamma-glutamyl phosphate reductase ADD19821.1 L-proline biosynthetic pathway

The thirty-two G. pallidipes proteins expressed in high abundance in the hypertrophied SGs at all the time points (0, 48, 72 and 96 hpf) but were either detected in very low abundance or not detectable at all in the non-hypertrophied salivary glands.