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. 2011 Nov 22;6(11):e27902. doi: 10.1371/journal.pone.0027902

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Dang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The QTL on chromosomes 2 (Lrag1) showed a significant linkage to aganglionosis severity, respectively. The dotted and thin lines represent suggestive (Su) and significant (Si) thresholds, respectively. The microsatellite markers used for determining genotypes of F₂ rats are presented along the X-axis. LRS, likelihood ratio statistic.