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. 2011 Nov 22;6(11):e27796. doi: 10.1371/journal.pone.0027796

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Bull et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Each of the three curves shows the profile of infection ‘ages’ at a specific stage of a culture, given as the approximate number of generations indicated (the number of generations associated with each curve is the number of transfers on 12 minute intervals). The 20-generations curve shows the approximate stable age distribution. Curves from earlier times indicate progressively greater deviations from stable age distribution. Infections were simulated as in Table 1. Parameters were chosen to match T7 values: the adsorption rate constant was mL/min, cell density was (assumed constant), was uniform across 9.3 to 11.5 minutes with a total burst size of 266.

Inline graphic — Each of the three curves shows the profile of infection ‘ages’ at a specific stage of a culture, given as the approximate number of generations indicated (the number of generations associated with each curve is the number of transfers on 12 minute intervals). The 20-generations curve shows the approximate stable age distribution. Curves from earlier times indicate progressively greater deviations from stable age distribution. Infections were simulated as in Table 1. Parameters were chosen to match T7 values: the adsorption rate constant was mL/min, cell density was (assumed constant), was uniform across 9.3 to 11.5 minutes with a total burst size of 266.