Figure 4. Oral treatment with Lc increases the number of CD4⁺FoxP3⁺ T_regs in MLNs.

No significant changes were found in spleen or Peyer's patches. The plots shows the expression of CD4 versus FoxP3 on gated Th cells (CD3⁺CD8⁻), and the values within the plots represent the mean ± standard deviation of the total numbers of CD4⁺FoxP3⁺ T cells from one representative experiment out of three independent experiments (3–5 mice per group). One-way ANOVA with Dunnett's multiple comparison test was used to evaluate the significance of differences in numbers of CD3⁺CD8⁻CD4⁺FoxP3⁺ cells between DSS/Lc-treated groups and the DSS/PBS-treated (control) group (*P<0.05).