Table 3.

Adjusted Comparisons of Baseline Functional Performance Measures and Two-Year Change in Functional Performance Measures with Mortality and Mobility Loss Among Participants with Peripheral Arterial Disease (N=446)

		Model I		Model II
Functional performance measures	Measurement	Standardized Hazard Ratio (95% Confidence Interval)	P value	Standardized Hazard Ratio (95% Confidence Interval)	P value
		Mobility Loss (N=324)
Six minute walk	Two-year change in performance.	0.86 (0.76 – 0.96)	0.01	0.82 (0.71 – 0.95)	0.007
	Baseline value	0.39 (0.30 – 0.51)	<0.001	0.31 (0.21 – 0.47)	<0.001
Four meter velocity, usual pace	Two-year change in performance.	0.74 (0.63 – 0.87)	<0.001	0.77 (0.66 – 0.92)	0.003
	Baseline value	0.23 (0.15 – 0.35)	<0.001	0.21 (0.12 – 0.35)	<0.001
Four meter velocity, fast pace	Two-year change in performance.	0.78 (0.67 – 0.89)	<0.001	0.80 (0.69 – 0.92)	0.002
	Baseline value	0.31 (0.22 – 0.43)	<0.001	0.29 (0.19 – 0.46)	<0.001
Short Physical Performance Battery	Two-year change in performance.	0.73 (0.64 – 0.85)	<0.001	0.70 (0.59 – 0.82)	<0.001
	Baseline value	0.34 (0.27 – 0.44)	<0.001	0.28 (0.20 – 0.40)	<0.001

		Model I		Model II
Functional performance measures	Measurement	Standardized Hazard Ratio (95% Confidence Interval)	P value	Standardized Hazard Ratio (95% Confidence Interval)	P value
		All-Cause Mortality (N=446)
Six minute walk	Two-year change in performance.	0.88 (0.81 – 0.97)	0.007	0.89 (0.81 – 0.97)	0.011
	Baseline value	0.61 (0.49 – 0.76)	<0.001	0.69 (0.53 – 0.90)	0.005
Four meter velocity, usual pace	Two-year change in performance.	0.89 (0.80 – 0.99)	0.026	0.93 (0.84 – 1.03)	0.166
	Baseline value	0.68 (0.54 – 0.86)	0.001	0.86 (0.66 – 1.11)	0.237
Four meter velocity, fast pace	Two-year change in performance.	0.82 (0.74 – 0.91)	<0.001	0.85 (0.77 – 0.95)	0.003
	Baseline value	0.69 (0.55 – 0.87)	0.001	0.84 (0.64 – 1.09)	0.179
Short physical performance battery	Two-year change in performance.	0.87 (0.79 – 0.97)	0.011	0.88 (0.79 – 0.99)	0.032
	Baseline value	0.68 (0.55 – 0.85)	<0.001	0.80 (0.62 – 1.04)	0.094

		Model I		Model II
Functional performance measures	Measurement	Standardized Hazard Ratio (95% Confidence Interval)	P value	Standardized Hazard Ratio (95% Confidence Interval)	P value
		Cardiovascular Disease Mortality (N=446)
Six minute walk	Two-year change in performance.	0.86 (0.75 – 0.99)	0.035	0.88 (0.75 – 1.02)	0.096
	Baseline value	0.58 (0.41 – 0.83)	0.003	0.72 (0.45 – 1.14)	0.161
Four meter velocity, usual pace	Two-year change in performance.	0.83 (0.71 – 0.97)	0.016	0.86 (0.72 – 1.02)	0.090
	Baseline value	0.69 (0.47 – 1.02)	0.062	0.93 (0.60 – 1.43)	0.738
Four meter velocity, fast pace	Two-year change in performance.	0.73 (0.63 – 0.85)	0.062	0.75 (0.63 – 0.90)	0.001
	Baseline value	0.70 (0.48 – 1.00)	0.052	0.96 (0.60 – 1.54)	0.875
Short physical performance battery	Two-year change in performance.	0.81 (0.69 – 0.96)	0.013	0.87 (0.72 – 1.05)	0.144
	Baseline value	0.71 (0.49 – 1.02)	0.067	0.95 (0.60 – 1.49)	0.809