Fig. 2.

Stars indicate the proteins of insulin signaling cascade affected by PPAR-γ agonists. Cbl Cbl protein, CAP Cbl-associated protein, IRS-1 insulin receptor substrate 1, Shc Shc protein, GRB2 growth factor receptor-bound protein 2, PI3K phosphatidylinositol 3-kinase, Akt Akt protein, GLUT4 glucose transporter 4, IR insulin receptor