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The TPVR- (A) and MBP- (B) response to 4-AP after inhibition of norepinephrine reuptake with desipramine. Significant responses (* within symbol) and group differences during the immediate TPVRmax (none detected) and after 25 min (brackets right of curve) were located as indicated. Desipramine reduced baseline TPVR in both strains and also MBP in WKY (Table 2). * – P ≤ 0.025.
