Table 2. Effects on fast ripples from changes in inactivation kinetics.
50Hz | 100Hz | |||||
---|---|---|---|---|---|---|
- | c | + | - | c | + | |
Without KA | 4 | 4 | 4 | 4 | 4 | 4 |
Fast ripple input | 0 | 0 | 3 | 0 | 0 | 3 |
Ripple input | 3 | 4 | 4 | 2 | 4 | 4 |
Number of spikes produced following fast ripple input (case 2). c control, standard value of the inactivation time constant i.e. same data as in figure 7 first and fourth column, + enhanced modulation by reducing the inactivation time constant by 4 ms representing enhanced KChIP/DPP modulation, - reduced modulation by increasing the inactivation time constant by 4 ms representing reduced KChIP/DPP modulation.