Table 3.

Relation of consistence of pain to risk of total knee replacement (TKR). Adjusted for age, sex, race, education, body mass index, depressive symptoms measured by CES-D, clinical site, occupation, and baseline cross-sectional radiographic Kellgren-Lawrence grade.

Consistency of frequent knee pain (FKP)	Total No. Knees	No. with TKR	Risk Over 30 Months	Adjusted Relative Risk Over 30 Months (95% CI)
No FKP	2937	24	0.8	1.0
Inconsistent FKP	1247	32	2.6	1.2 (0.6–2.3)
Consistent FKP	1669	146	8.8	2.3 (1.2–4.4)