Figure 5. Overexpression of NIK in T cells causes lethal inflammation.
(A and B) CD4-NIKtg and age-matched littermate WT control mice were weighed and euthanized when moribund. Data in A show average weights (± SD) from 2 combined litters. (C) Sections of colon and lungs from moribund CD4-NIKtg and age-matched littermate WT control mice were assessed for leukocyte infiltrates by hematoxylin-eosin stain. Scale bars: 100 μm. Data are from 2 combined litters.