Figure 5.

Phylogenetic tree of hexose transporter family proteins identified in S288C. The amino acid sequences of S288C HXT gene products were clustered by CLUSTALW 1.83, and the dendrogram was plotted using the TreeView program. Symbols at the end of the branches indicate the structural class of K7 orthologous gene products, as shown in the box under the dendrogram. Two groups of Hxts, whose functional structures were disrupted in K7, are framed with rectangles. Underlines indicate genes whose expression is repressed under high-glucose conditions. The letter (a) denotes each of the two K7 orthologs is indicated as a half round.