Table 1. Comparative summary statistics for demographic, clinical and laboratory data.
Nevirapine-based HAART (n = 89) | Efavirenz-based HAART (n = 30) | P-value | |
Age in years | 31.4 (28.3–36.5) | 32.6 (28.9–37.7) | 0.258 |
Female | 81 (91%) | 25 (83%) | 0.200 |
CDC stage B or C | 30 (34%)(n = 88) | 13 (46%)(n = 28) | 0.267 |
CD4 count (cells/mm3) | 241 (173–359) | 159 (110–265) | 0.005 |
HIV RNA (log10 copies/mL) | 3.70 (3.28–4.09) | 3.99 (3.75–4.69) | 0.007 |
CRF01_AE | 84 (94%) | 29 (97%) | |
Exposure to single-dose nevirapine | 58 (81%) | 10 (56%) | 0.036 |
Time (days) from single-dose nevirapine to HAART initiation | 139 (64–397) | 387 (125–505) | 0.299 |
ZDV backbone | 20(22%) | 15(50%) | 0.006 |
d4T backbone | 60(67%) | 5(17%) | <0.001 |
TDF backbone | 9(10%) | 10(33%) | 0.007 |
3TC backbone | 82(92%) | 19(63%) | <0.001 |
FTC backbone | 7(8%) | 10(33%) | 0.001 |
Estimated duration (days) of virologic failure before HIV resistance genotype testing | 91 (42–189) | 93 (56–196) | 0.743 |
Time (days) from HAART initiation to virologic failure | 238 (112–609) | 212 (88–441) | 0.530 |
All figures are medians (interquartile ranges) or number (percent).