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. 2011 May 3;16(12):1177–1188. doi: 10.1038/mp.2011.48

Figure 5.

Figure 5

Fluoxetine-induced improvement of the HPA axis negative feedback under chronic stress conditions involves hippocampal neurogenesis. (a) Schematic representation of the experimental design. (b) Schedule of the fecal sample collection and of the dexamethasone-phosphate (DEX-P) administration. (c) The DEX suppression test allowed assessing the integrity of the HPA axis negative feedback. The figure shows the DEX-induced suppression of fecal corticosterone metabolites (CORT), n=8–11 per group. #P<0.05 UCMS-vehicle mice vs control-vehicle mice; *P<0.05 and **P<0.01 UCMS-fluoxetine mice vs UCMS-vehicle mice, or between line-connected groups. Data represent mean±s.e.m.