Table 3.
Correlation analysis between HIF-1α expression and GLUT-1, ER, PR, HER2 and tumor type and grade (chi-square test). NB: Not all stainings could be successfully performed for all cases
| HIF-1α overexpression | ||||
|---|---|---|---|---|
| Negative | Positive | P value | ||
| GLUT-1 | Negative | 37 | 31 | 0.1 |
| Positive | 8 | 16 | ||
| ER | Negative | 2 | 10 | 0.03 |
| Positive | 42 | 37 | ||
| PR | Negative | 15 | 22 | 0.3 |
| Positive | 28 | 25 | ||
| HER2 | Negative | 44 | 43 | 1 |
| Positive | 1 | 2 | ||
| CAIX | Negative | 27 | 11 | <0.01 |
| Positive | 18 | 36 | ||
| Grade | 1 | 25 | 11 | 0.00 |
| 2 | 16 | 14 | ||
| 3 | 4 | 22 | ||
| Type | Ductal/metaplastic | 26 | 36 | 0.05 |
| Tubular/lobular/cribriform | 19 | 11 | ||