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. 2011 Nov 24;2:83. doi: 10.3389/fphys.2011.00083

Table 1.

Anatomical and hemodynamical data measured with closed-chest.

SHAM (n = 12) MI (n = 12)
ANATOMICAL DATA
BW (kg) 30 ± 1 30 ± 1
LV weight (g) 88 ± 5 102 ± 3*
LV weight/BW (g/kg) 2.9 ± 0.1 3.5 ± 0.1*
LV end-diastolic area (mm2) 913 ± 54 1342 ± 133*
LV end-systolic area (mm2) 426 ± 37 830 ± 114*
2D-Ejection fraction (%) 53 ± 3 39 ± 4*
HEMODYNAMIC DATA
Cardiac output (L/min) 3.7 ± 0.3 3.0 ± 0.1*
Heart rate (HR, bpm) 112 ± 5 124 ± 12
Mean aortic pressure (mmHg) 92 ± 5 98 ± 4
Mean pulmonary artery pressure (mmHg) 18 ± 1 28 ± 2*
LVdP/dtmax (mmHg/s) 2002 ± 119 1717 ± 68*
LVdP/dtmin (mmHg/s) −2199 ± 164 −1915 ± 104
Tau (ms) 34 ± 1 45 ± 4*
LV end-diastolic pressure (mmHg) 6 ± 2 15 ± 2*

n, Number of animals; BW, body weight; LV, left ventricle. *P < 0.05; MI vs. sham in one-tailed Student’s t-test.