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. 2011 Nov 7;108(47):19007–19012. doi: 10.1073/pnas.1109066108

Fig. 2.

Fig. 2.

Structure of mouse NKT TCRs in complex with mouse CD1d-αGalCer. (A) Vα14Vβ2 NKT TCR-CD1d-α-GalCer. Magenta, α-GalCer; gray, CD1d heterodimer; cyan, Vα14; pink, Vβ2; purple, CDR1α; yellow, CDR3α; teal, CDR1β; ruby, CDR2β; orange, CDR3β. (B) Vα14Vβ8.2 NKT TCR-CD1d-α-GalCer (14) [Protein Data Bank (PDB) reference ID 3HE6]. Green, Vβ8.2. α-GalCer, CD1d, Vα14, and CDR loops color coding as in A. (C) Vα14Vβ7 NKT TCR-CD1d-α-GalCer (14) (PDB reference ID 3HE7). Dark blue, Vβ7; α-GalCer, CD1d, Vα14, and CDR loops color coding as in A. (D) Superposition of Vβ2, Vβ8.2, and Vβ7 NKT TCR-CD1d-α-GalCer. Color coding as in A to C. (E) Footprint of Vα14Vβ2 on the surface of CD1d-α-GalCer. α-GalCer is shown in spheres. (F) Footprint of Vα14Vβ8.2 on the surface of CD1d-α-GalCer. (G) Footprint of Vα14Vβ7 on the surface of CD1d-α-GalCer. E to G color coding is the same as in A.