Fig. 4.

The effect of serotonin on the synchrony of bursting in the dorsal and ventral branches of the ventral root during fictive swimming. (A) Example of bursting before and after addition of serotonin to the bath. After serotonin, the dorsal and ventral branches were not as well synchronized as in the control. (B) After rectifying and smoothing the bursts of the ventral root, the waveforms of the dorsal and ventral branches were used to create a cross-correlogram. An epoch of 100 s was used for the correlogram. The peak-to-trough CCF was lower after adding the serotonin. (C) A plot of the time course of the fall in the peak-to-trough CCF (i.e., the degree of burst synchrony) after adding serotonin to the bath. (D) In seven preparations, the mean peak-to-trough CCF decreased significantly after adding serotonin (5-HT). (*P < 0.001; paired t-test).