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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: J Oral Maxillofac Surg. 2012 May;70(5):1081–1092. doi: 10.1016/j.joms.2011.05.002

Figure 3. Effects of pamidronate on alveolar osteoblast osteogenesis.

Figure 3

Figure 3

Figure 3

(A, B) Quantitative assessments of AP activity indicated significant decrease at higher pamidronate concentrations (#, p<0.01) (*, p< 0.001). The cells were cultured 168h in unsupplemented medium (CM) and in medium with osteogenic supplements (OM). Data represent averages ± SD of measurements (n=4) obtained from two alveolar bone samples. (C) Histological stains (Fast Blue RR Salt) indicated a decrease in the number of cells strongly expressing AP activity (black arrows) at higher pamidronate concentrations. Magnification 100×.