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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: J Phys Chem B. 2011 Nov 8;115(47):13911–13924. doi: 10.1021/jp206963g

Figure 2.

Figure 2

Schematic of all reaction paths possible in hairpin ribozyme self-cleavage. Physically less meaningful pathways involving unlikely protonation states (at pH ~7) of the phosphate or 2’-OH nucleophilic group in precursor or product state (gray background) were not considered in this study.