Table 2.
Mass Spectrometry Results Showing Plasma Concentrations of G6 at Euthanasia of Jak2-V617F Transgenic Mice.
| Animal ID | Plasma* (µg/ml) |
| Vehicle Treated | |
| 1 | <0 |
| 2 | <0 |
| 3 | <0 |
| 4 | <0 |
| 5 | <0 |
| 6 | <0 |
| G6 Treated | |
| 1 | 48.6 |
| 2 | 0.155 |
| 3 | 0.036 |
| 4 | 0.025 |
| 5 | 0.030 |
| 6 | ND |
*
Standard curve was quadratic (1/x2), r = 0.9902 with range from 0.005 to 5.00 µg/ml. Shown is the average of replicate injections. Calculations were done using Analyst Software 1.4.2 (AB Sciex, Foster City, CA). Less than zero (<0) indicates peak quantities below the 0 value of the standard curve. ND indicates that value was not determined because of insufficient sample quantity at the time of analysis.