Figure 2. Comparison of nitisinone- and vehicle-treated Tyr^c-2J/c-2J and Tyr^c-h/c-h mice.

(A) WT C57BL6 mouse. (B and C) Untreated (U) and treated (T) Tyr^c-2J/c-2J (B) and Tyr^c-h/c-h (C) mice at 1 month. A patch of fur was shaved to stimulate new hair growth, which was preferentially pigmented. (D and E) Close-up images of previously shaved areas of untreated and treated Tyr^c-h/c-h mice.