r |
births per year |
0.0127 |
r = d2(d1 + f)/(d2 + f) |
f |
maturity rate |
1/19 |
|
d1
|
juvenile death rate |
20/100 000 |
US Census, CDC/NCHS |
d2
|
adult death rate |
1/55 |
ks,1
|
juvenile death rate from varicella (no vaccine) |
1/100 000 |
[3] |
ks,2
|
adult death rate from varicella (no vaccine) |
20/100 000 |
kv,1
|
varicella mortality of vaccinated juveniles |
1/10 000 000 |
[1] |
kv,2
|
varicella mortality of vaccinated adults |
20/10 000 000 |
σ |
1/duration of incubation period |
26 |
[16] |
δs
|
1/duration of infectious period (no vaccine) |
52 |
δv
|
1/duration of infectious period if vaccinated |
81 |
[17] |
β1
|
transmission rate—juveniles to juveniles |
1760 |
based on Ro = 9.4 and the probability (approx. 90%) of acquiring varicella by age 20 prior to the availability of vaccine |
β2
|
transmission rate—adults to adults, adults to juveniles and juveniles to adults |
250 |
v |
vaccination probability |
(variable of interest) |