Figure 4.

Low-dose DBD plasma treatment enhanced two-dimensional endothelial cell migration, which was abrogated by FGF-2 and ROS blockade. (a) PAEC migration after 4.2 J cm^–2 plasma treatment was assessed using a cage assay, with and without an FGF-2 neutralizing antibody. Migration distance was assessed by phase contrast microscopy 0, 24, 48 and 72 h after treatment. ^† p < 0.001 compared with control. *p < 0.01, ^††p < 0.001. #p < 0.001 compared with FGF-2 (10 ng ml^–1). (b) NAC and SP were used to block intracellular and extracellular ROS. *p < 0.01, ^†p < 0.001.