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. 2011 Apr 13;9(66):1–19. doi: 10.1098/rsif.2011.0301

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This journal is © 2011 The Royal Society

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Transplantation of bone marrow cells into infarcted myocardium in humans. The balloon catheter enters the infarct-related artery and is placed above the border zone of the infarction. The catheter is then inflated and the cell suspension (including the patient's own cytokines) is infused at high pressure under stop-flow conditions. In this way, cells are transplanted into the infarcted zone through the infarct-related vessel system. Cells and cytokines infiltrate the infarcted zone. The arrows show the possible route of cell migration and cytokine infiltration. LAD, left anterior descending coronary artery; LCX, left circumflex artery; RCA, right coronary artery [112].