Table 2.

Lithium in clinical trials as a potential neuroprotector.

Institution	Phase	Trial	Study population	Treatment
New York University School of Medicine	II	NCT01105702	Newly diagnosed high grade glioma (WHO Grade III and IV)	Temodar (Temozolomide), Bevacizumab, lithium, and radiation for high grade glioma
Vanderbilt-Ingram Cancer Center	I	NCT00469937	–Histopathologically confirmed extracranial primary malignancy	Lithium during whole brain radiotherapy for patients with brain metastases
			–Multiple (i.e., >3) brain metastases OR < 3 metastases with at least 1 metastasis >4.0 cm in diameter
			–Not eligible for radiosurgery
			–No requirement for immediate whole-brain radiotherapy
			–No metastases to the midbrain or brainstem

Information from www.Clinicaltrials.gov accessed on August 1, 2011.

*Italicized = completed trials.