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. 2011 Jun 13;121(7):2736–2749. doi: 10.1172/JCI45444

Figure 4. KLF4-deficient macrophages exhibit enhanced bactericidal activity.

Figure 4

(A and B) KLF4-deficient macrophages exhibit enhanced bactericidal activity against E. coli ex vivo. n = 3 in each group. (C–G) Expression of genes involved in bactericidal activity is augmented in KLF4-deficient macrophages after incubation with E. coli. n = 3 in each group. (H) NO production in macrophage was determined by nitrite (NO2–) levels in conditioned medium. n = 3 in each group. *P < 0.05, Student’s t test with Bonferroni correction.