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. 2011 Jun 23;121(7):2845–2854. doi: 10.1172/JCI57324

Figure 10. Renal dopamine deficiency was associated with shorter life spans.

Figure 10

(A) At 20 months of age, 10 out of 19 ptAadc–/– mice had died, while only 1 out of 20 wild-type mice had died. (B) Immunoblotting showed reduced levels of prosurvival genes Sirt3 and PBEF in ptAadc–/– mice.