Figure 2. KD leads to downregulation of ADK.

(A) Representative Western blot from brain extracts of WT mice fed CD or KD for 3 and 4 weeks. Note the 2 different splice variants of ADK in the ADK-reactive bands. Anti-tubulin immunoreactivity was used to normalize for equal loading. Lanes were run on the same gel but were noncontiguous (white line). (B) Brain ADK from mice fed CD or KD for 3–4 weeks, expressed relative to CD (n = 4 per group). Data are mean ± SEM. **P < 0.01 vs. CD.