TABLE 3.
Multivariable regression analysis of the l-arginine:ADMA ratio in 1138 healthy individuals of the Framingham Offspring Cohort1
Variable2 | β ± SE3 | P value |
Homocysteine | −1.21 ± 0.37 | 0.001 |
log CRP | −2.35 ± 1.02 | 0.022 |
Glomerular filtration rate | 0.09 ± 0.04 | 0.035 |
DBP | 0.31 ± 0.15 | 0.037 |
ADMA, asymmetric dimethylarginine; CRP, C-reactive protein; DBP, diastolic blood pressure; SBP, systolic blood pressure.
Candidate variables that were considered for model entry were age, sex, BMI, SBP, DBP, the total:HDL ratio, alcohol consumption, TG, glomerular filtration rate, homocysteine, fasting glucose, and CRP.
All regression coefficients (β estimates) represent the estimated mean change in l-arginine:ADMA ratio per 1-unit increase in the corresponding covariate.