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. 2011 Nov;16(9):554–556. doi: 10.1093/pch/16.9.554

TABLE 2.

Factors contributing to drug-induced esophageal injury

Patient Pharmaceutical
Recumbence after ingestion of medication Concentration of medication
Insufficient fluid taken with medication pH of medication
Decreased saliva production Slow-release format
Prolonged contact of medication with mucosa Delivery method (capsule versus tablet)
Esophageal disorders Tablet size

Data from reference 3