Fig. 6.
Intrinsic threshold and inward rectification of spiral ganglion neurons showed a non-monotonic distribution pattern, with elevated sensitivity and inward rectification positioned in the mid-apical spiral ganglion. a, Current clamp traces illustrate an inverse relationship between threshold voltage (red arrowheads) and hyperpolarizing sag magnitude (blue arrowheads): the higher the threshold (left to right), the lower the sag magnitude. Dashed lines indicate their highest (−45.8mV) and lowest (−57.6mV) threshold levels. Holding potential: −80mV; hyperpolarization peak: −185mV. b & c: hyperpolarizing sag magnitude (b) and threshold (c) plotted as a function of location in gangliotopic and neuronal cultures. Adapted from Liu and Davis, 2007.