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. 2011 Jun 13;12:233. doi: 10.1186/1471-2105-12-233

Figure 1.

Figure 1

Gene regulatory network model. In this gene regulatory network model, a layer of Activated Transcription Factors added between the Transcription Factors layer and Gene layer. Only activated transcription factors can regulate the expression of genes through the gene regulatory links, inactivated transcription factors do not have regulatory links to the target genes. And the expression level of genes regulated by activated transcription factors changes by the effect of regulation, and the changed expression levels of genes affect the amount of the translated transcription factors.