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. 2011 Sep 29;12:384. doi: 10.1186/1471-2105-12-384

Table 1.

Power calculation under Scenario (A)

Strategy Corr MAF Method

LR FPM TPM Lasso Enet GRLR
I 0.0 0.10 0.196 0.206 0.198 0.210 0.226 0.196
0.30 0.638 0.620 0.602 0.688 0.670 0.650
0.50 0.792 0.734 0.730 0.790 0.828 0.826
0.2 0.10 0.184 0.216 0.194 0.194 0.204 0.206
0.30 0.712 0.642 0.622 0.690 0.726 0.704
0.50 0.860 0.794 0.788 0.902 0.888 0.870

II 0.0 0.10 0.008 0.078 0.070 0.032 0.052 0.124
0.30 0.122 0.266 0.252 0.340 0.392 0.558
0.50 0.354 0.304 0.306 0.526 0.624 0.768
0.2 0.10 0.018 0.088 0.064 0.066 0.078 0.126
0.30 0.202 0.296 0.300 0.364 0.458 0.608
0.50 0.400 0.370 0.360 0.628 0.690 0.806

Results of power simulations for six methods under Scenario (A) (two causal SNPs). Two definitions of testing success, Strategy I (requiring that at least one of the two SNPs is significant) and Strategy II (requiring significance at both SNPs), are applied in comparisons; The number of replication runs is 500 for all the simulations. Corr = correlation coefficient; MAF = minor allele frequency.