Table 5.
Rank | Chr | SNP rs# | Bp Position | Odds Ratio | Original P-value | Bonferroni Correction | Empirical P-value |
---|---|---|---|---|---|---|---|
1 | 10 | rs10490924 | 124204438 | 0.26 | 1.25E-09 | 0.0001 | 0.001 |
2 | 8 | rs10504152 | 54292668 | 0.18 | 5.45E-06 | 0.4428 | 0.062 |
3 | 7 | rs10499342 | 4340896 | 0.36 | 3.88E-05 | 1.0000 | 0.550 |
4 | 13 | rs2011847 | 69496879 | 0.42 | 5.86E-05 | 1.0000 | 0.738 |
5 | 8 | rs1377131 | 53838124 | 3.09 | 7.49E-05 | 1.0000 | 0.836 |
6 | 4 | rs10520462 | 182400252 | 3.21 | 8.73E-05 | 1.0000 | 0.888 |
7 | 1 | rs1564485 | 53333649 | 0.41 | 1.10E-04 | 1.0000 | 0.940 |
8 | 5 | rs10521010 | 33931083 | 3.03 | 1.17E-04 | 1.0000 | 0.943 |
9 | 5 | rs251610 | 65314237 | 0.45 | 1.55E-04 | 1.0000 | 0.980 |
10 | 20 | rs1858597 | 95685 | 0.42 | 1.66E-04 | 1.0000 | 0.987 |
Analysis results for the published dataset on AMD Hong Kong using logistic regression. Odds ratios, original p-values, p-values after Bonferroni correction, and empirical p-values (derived from 1000 permutations) of the top 10 SNPs are listed.