Table 2.
The association of the Klotho KL-VS variant with echocardiographic evidence of mitral annular or aortic valve calcificationa
| SNP | Genotype | Cases, N (%) | Controls, N (%) | OR (95% CI) | OR (95% CI) adjusted for age and sex |
| rs9536314 | TT | 900 (65) | 1404 (66) | Ref | Ref |
| TG | 455 (33) | 663 (31) | 0.93 (0.81–1.08) | 0.90 (0.77–1.05) | |
| GG | 34 (2) | 72 [22] | 1.36 (0.90–2.06) | 1.29 (0.84–2.01) | |
| TT | 900 (65) | 1404 (66) | Ref | Ref | |
| TG/GG | 489 (35) | 735 (34) | 0.96 (0.84–1.11) | 0.93 (0.80–1.08) | |
| TT/TG | 1355 (98) | 2069 (97) | Ref | Ref | |
| GG | 34 (2) | 72 [22] | 1.39 (0.92–2.10) | 1.34 (0.87–2.07) |
a
CI, confidence interval.