Table 3.

The Klotho KL-VS variant and its effects on cardiac and aortic calcification^a

	TT	TG	GG	Additive P-value	Recessive P-value	Dominant P-value
Echocardiographic calcification
N	2004	1003	99
% Aortic valve calcification	0.6	0.8	2	0.24	0.11	0.33
N	2051	452	32
% Mitral annular calcification	44	46	34	0.81	0.06	0.33
Calcification scores [21]
N	886	423	38
Aortic valve	0	0	0	0.99	0.88	0.99
IQR	0–193.7	0–197.2	0–188.6
N	886	423	38
Mitral valve	0	0	0	0.98	0.89	0.40
Range	0–494.3	0–674.1	0–312.1
N	840	407	38
Coronary artery	36.2	41.3	27.5	0.81	0.77	0.61
IQR	0–257.8	0–235.4	0–448.4
N	895	364	38
Aortic artery	616.8	812.5	406.9	0.38	0.18	0.93
IQR	19.9–2962.3	52.2–2263.3	0–1684.2

^aIQR, interquartile range.