Table 4.

Additional SNPs examined for Klotho β-Klotho and FGF-23^a

			HWE
Gene	SNP	MAF	Chi-square	P-value
Klotho	rs562020	0.34	0.31	0.58
	rs385564	0.33	1.20	0.27
	rs576404	0.40	1.13	0.29
	rs571118	0.47	0.15	0.70
	rs516306	0.38	1.04	0.31
	rs9526983	0.08	6.09	0.01
	rs684492	0.32	0.60	0.44
	rs684868	0.32	0.58	0.44
	rs553791	0.32	0.55	0.46
	rs554634	0.32	0.50	0.48
	rs9527024	0.17	0.15	0.70
	rs9536313	0.17	0.11	0.74
	rs9527025	0.17	0.0007	0.98
	rs648202	0.14	0.18	0.67
β-Klotho	rs900563	0.19	1.24	0.27
	rs12647895	0.19	4.63	0.03
	rs1982738	0.24	0.10	0.75
	rs11940694	0.40	0.24	0.63
	rs1979283	0.34	1.56	0.21
	rs2608819	0.12	0.83	0.36
	rs6854452	0.29	5.27	0.02
	rs1458254	0.15	3.80	0.05
	rs4975017	0.29	4.17	0.04
FGF-23	rs11063112	0.30	0.43	0.51
	rs7955866	0.11	2.68	0.10
	rs13312789	0.12	5.94	0.01

^aSNP, single nucleotide polymorphisms; MAF, minor allele frequency; HWE, Hardy–Weinberg equilibrium; SNPs rs9527023 and rs649964 were genotyped but not analyzed due to >10% missing genotype data; SNPs rs3752472, rs649964 and rs649964 were genotyped but not analyzed due to a MAF ≤0.2%.