Table 2.
Antimicrobial resistance gene products encoded by A.baumannii genomes
| Gene Products | Strains | ||||||
|---|---|---|---|---|---|---|---|
| AB0057 | AYE | 3990 | ACICU | 4190 | ATCC17978 | 3909 | |
| Class C β-lactamase | 9, 2796 | 1110 | 2437 | 2564 | 2076 | 2367 | 1404 |
| Class A β-lactamase | 283 (TEM-1) | - | - | - | - | - | - |
| - | 3623 (VEB-1) | - | - | - | - | - | |
| Class D β-lactamase | 1757 (oxa-69) | 2122 (oxa-69) | 2827 (oxa-66) | 1560 (oxa-66) | 63 (oxa-64) | 1517 (oxa-95) | 1089 (oxa-90) |
| - | - | 3514 (oxa-20) | 0226 (oxa-20) | - | - | - | |
| 0551 (oxa-23)* | - | - | - | - | - | - | |
| - | - | p2ABST2 (oxa-58)* | pACICU1 (oxa-58)* (2X) |
p1ABST25 (oxa-72)* | - | p1ABST78 (oxa-58)* | |
| - | - | - | - | p2ABST25 (oxa-72)* | - | - | |
| AAC (3)-I aminoglycoside acetyltransferase | 291 | 3573 | - | - | - | - | - |
| AAC (6')-I aminoglycoside acetyltransferase | - | 3630 | 3516 | 223 | - | - | - |
| APH (3')-I aminoglycoside phosphotransferase | 288 | 3578 | - | - | - | - | - |
| - | - | 3897 | 1948 | 560 | - | - | |
| ANT (3'')-I aminoglycoside adenylyltransferase | 293 | 3570,3618 | - | - | 3268 | - | - |
| 171 | 3739 | 1641 | 156 | 2954 | 131 | 2919 | |
| Chloramphenicol acetyl transferase | 280 | 3587 | - | - | - | - | - |
| 3104 | 798 | 3709 | 2932 | 1731 | 2691 | 1443 | |
| DNA topoisomerase II | 3037 [R1] | 0867 [R1] | 0747 [R1] | 2869 [R1] | 2907 [R1] | 2626 [S] | 0539 [R1] |
| DNA topoisomerase IV | 0232 [R2] | 3679 [R2] | 1415 [S] | 0214 [S] | 2382 [R2] | - | 3413 [R2] |
| RNA polymerase β Subunit | 0369 [S] | 3489 [S] | 2179 [R3] | 0303 [S] | 3155 [S] | 0287 [S] | 0411 [S] |
| Dihydropteroate synthase | 265, 294 | 3568,3616,3612 | 3142 | 228 | - | 675 | - |
| 3095 | 807 | 3700 | 2923 | 2684 | 2680 | 1433 | |
| Dihydrofolate reductase type 1 | - | 3644 | - | - | - | - | - |
| Dihydrofolate reductase type 3 | 540 | 3315 | 3351 | 467 | 3501 | 457 | 403 |
R, resistant; S, susceptible; R1 81 Ser →Leu; R2 84 Ser → Leu; R 3 535 His → Leu; * carbapenem-hydrolysing class D beta-lactamase; + ORFs identified by tBLASTn.